622795-76-0
622795-76-0 structure
- Name: PIP-199
- Chemical Name: PIP-199
- CAS Number: 622795-76-0
- Molecular Formula: C27H28N4O3
- Molecular Weight: 456.54
- Create Date: 2021-01-12 23:06:11
- Modify Date: 2025-08-25 14:23:21
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PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. MM2 is the binding site of RMI complex on Fanconi anemia complementation group M protein (FANCM). PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics.
| Name | PIP-199 |
|---|---|
| Synonyms | MFCD04443596 |
| Description | PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. MM2 is the binding site of RMI complex on Fanconi anemia complementation group M protein (FANCM). PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics. |
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| Molecular Formula | C27H28N4O3 |
|---|---|
| Molecular Weight | 456.54 |
| Storage condition | -20°C |
| Hazard Codes | Xi |
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