1254044-41-1
1254044-41-1 structure
- Name: Mito-apocynin (C2)
- Chemical Name: Mito-apocynin (C2)
- CAS Number: 1254044-41-1
- Molecular Formula: C28H27BrNO3P
- Molecular Weight: 536.40
- Catalog: Research Areas Neurological Disease
- Create Date: 2020-06-01 12:39:25
- Modify Date: 2024-01-31 17:41:00
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Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect[1].
| Name | Mito-apocynin (C2) |
|---|
| Description | Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect[1]. |
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| Related Catalog | |
| In Vivo | Mito-apocynin (C2) (3 mg/kg; p.o.; daily for 12 days) exhibits antineuroinflammatory effect[1]. Animal Model: MPTP mice model of Parkinson’s Disease[1] Dosage: 3 mg/kg Administration: Oral gavage; daily for 12 days Result: Significantly attenuated MPTP-induced glial cell activation, proinflammatory cytokine upregulation, inducible nitric oxide synthase, and NOX2 components (gp91phox). |
| References |
| Molecular Formula | C28H27BrNO3P |
|---|---|
| Molecular Weight | 536.40 |