1620461-89-3

1620461-89-3 structure

1620461-89-3 structure

Name: mPEG12-Br
Chemical Name: m-PEG12-Br
CAS Number: 1620461-89-3
Molecular Formula: C₂₅H₅₁BrO₁₂
Molecular Weight: 623.57
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:13:04
Modify Date: 2024-01-10 15:17:11
m-PEG12-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG12-Br

Description	m-PEG12-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₅H₅₁BrO₁₂
Molecular Weight	623.57