2168540-50-7

2168540-50-7 structure
2168540-50-7 structure
  • Name: m-PEG12-COO-propanoic acid
  • Chemical Name: m-PEG12-COO-propanoic acid
  • CAS Number: 2168540-50-7
  • Molecular Formula: C29H56O16
  • Molecular Weight: 660.75
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 05:40:02
  • Modify Date: 2024-01-10 10:19:57
  • m-PEG12-COO-propanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG12-COO-propanoic acid
Description m-PEG12-COO-propanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C29H56O16
Molecular Weight 660.75