DC Chemicals Limited
China
Product Name: ERAP1-IN-1
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Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

865273-97-8

865273-97-8 structure

865273-97-8 structure

Name: ERAP1-IN-1
Chemical Name: ERAP1-IN-1
CAS Number: 865273-97-8
Molecular Formula: C₂₀H₂₁F₃N₂O₅S
Molecular Weight: 458.45
Catalog: Research Areas Inflammation/Immunology
Create Date: 2020-01-23 22:03:51
Modify Date: 2024-01-11 16:30:09
ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates[1].

Name	ERAP1-IN-1

Description	ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	ERAP1[1]
In Vitro	ERAP1-IN-1 allosterically activates ERAP1’s hydrolysis of fluorogenic and chromogenic amino acid substratesv[1]. ERAP1-IN-1 (50 µM) exhibits specific inhibition of ERAP1 in the cellular context[1].
References	[1]. Maben Z, et al. Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1. J Med Chem. 2019 Dec 30.

Molecular Formula	C₂₀H₂₁F₃N₂O₅S
Molecular Weight	458.45

Hazard Codes	Xi