1335138-62-9
1335138-62-9 structure
- Name: DS-1040
- Chemical Name: DS-1040
- CAS Number: 1335138-62-9
- Molecular Formula: C16H27N3O2
- Molecular Weight: 293.411
- Create Date: 2020-01-11 18:05:50
- Modify Date: 2024-08-13 12:05:20
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DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile Stroke Phase 2 Clinical
| Name | DS-1040 |
|---|
| Description | DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile Stroke Phase 2 Clinical |
|---|---|
| References | References 1. Zhou J, et al. J Thromb Haemost. 2017 May;15(5):961-971. 2. Gurewich V, et al. J Thromb Haemost. 2017 Oct;15(10):2080-2081. 3. Paul A Lapchak, et al. Abstract WP282: DS-1040 an Inhibitor of the Activated Thrombin Activatable Fibrinolysis Inhibitor Improves Behavior in Embolized Rabbits, Stroke. 2016;47:AWP282. View Related Products by Target Other Targets Stroke |
| Molecular Formula | C16H27N3O2 |
|---|---|
| Molecular Weight | 293.411 |