DS-1040
Modify Date: 2023-01-16 16:56:24
DS-1040 structure
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Common Name | DS-1040 | ||
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| CAS Number | 1335138-62-9 | Molecular Weight | 293.411 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H27N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DS-1040DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile Stroke Phase 2 Clinical |
| Name | DS-1040 |
|---|
| Description | DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile Stroke Phase 2 Clinical |
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| References | References 1. Zhou J, et al. J Thromb Haemost. 2017 May;15(5):961-971. 2. Gurewich V, et al. J Thromb Haemost. 2017 Oct;15(10):2080-2081. 3. Paul A Lapchak, et al. Abstract WP282: DS-1040 an Inhibitor of the Activated Thrombin Activatable Fibrinolysis Inhibitor Improves Behavior in Embolized Rabbits, Stroke. 2016;47:AWP282. View Related Products by Target Other Targets Stroke |
| Molecular Formula | C16H27N3O2 |
|---|---|
| Molecular Weight | 293.411 |