Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Abemaciclib Metabolites M2
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

1231930-57-6

1231930-57-6 structure

1231930-57-6 structure

Name: Abemaciclib Metabolites M2
Chemical Name: Abemaciclib Metabolites M2
CAS Number: 1231930-57-6
Molecular Formula: C₂₅H₂₈F₂N₈
Molecular Weight: 478.54
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2019-06-30 11:20:15
Modify Date: 2025-08-26 18:02:31
Abemaciclib Metabolites M2 is a metabolite of abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s in the range of 1-3 nM. Anti-cancer activity[1].

Name	Abemaciclib Metabolites M2

Description	Abemaciclib Metabolites M2 is a metabolite of abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s in the range of 1-3 nM. Anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK4:1-3 nM (IC50) CDK6:1-3 nM (IC50)
References	[1]. Teresa Burke, et al. Abstract 2830: The major human metabolites of abemaciclib are inhibitors of CDK4 and CDK6. Cancer Research. July 2016, 76 (14).

Molecular Formula	C₂₅H₂₈F₂N₈
Molecular Weight	478.54

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.