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2075629-81-9

2075629-81-9 structure
2075629-81-9 structure
  • Name: PF-06795071
  • Chemical Name: PF-06795071
  • CAS Number: 2075629-81-9
  • Molecular Formula: C18H17F4N3O3
  • Molecular Weight: 399.34
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease MAGL
  • Create Date: 2019-03-30 16:01:33
  • Modify Date: 2024-01-27 17:19:25
  • PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM[1].

Name PF-06795071
Description PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM[1].
Related Catalog
Target

IC50: 3 nM (MAGL)[1]

In Vitro PF-06795071 shows excellent selectivity against FAAH with an IC50 of 3.1 μM[1].
References

[1]. McAllister LA, et al. Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. J Med Chem. 2018 Apr 12;61(7):3008-3026.

Molecular Formula C18H17F4N3O3
Molecular Weight 399.34
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