DC Chemicals Limited
China
Product Name: PF-06795071
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2075629-81-9

2075629-81-9 structure

2075629-81-9 structure

Name: PF-06795071
Chemical Name: PF-06795071
CAS Number: 2075629-81-9
Molecular Formula: C₁₈H₁₇F₄N₃O₃
Molecular Weight: 399.34
Catalog: Signaling Pathways Metabolic Enzyme/Protease MAGL
Create Date: 2019-03-30 16:01:33
Modify Date: 2024-01-27 17:19:25
PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM[1].

Name	PF-06795071

Description	PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	IC50: 3 nM (MAGL)[1]
In Vitro	PF-06795071 shows excellent selectivity against FAAH with an IC50 of 3.1 μM[1].
References	[1]. McAllister LA, et al. Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. J Med Chem. 2018 Apr 12;61(7):3008-3026.

Molecular Formula	C₁₈H₁₇F₄N₃O₃
Molecular Weight	399.34