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1801151-09-6

1801151-09-6 structure
1801151-09-6 structure
  • Name: BMS-986163
  • Chemical Name: BMS-986163
  • CAS Number: 1801151-09-6
  • Molecular Formula: C23H28FN2O5P
  • Molecular Weight: 462.45
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
  • Create Date: 2019-03-31 01:20:33
  • Modify Date: 2024-02-08 21:58:17
  • BMS-986163 is a negative allosteric modulator of GluN2B. The prodrug BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).

Name BMS-986163
Description BMS-986163 is a negative allosteric modulator of GluN2B. The prodrug BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).
Related Catalog
Target

IC50: 4 nM (GluN2B, BMS-986169), 24 nM (GluN2B, BMS-986169)[1]

References

[1]. Marcin LR, et al. BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive Disorder. ACS Med Chem Lett. 2018 Apr 13;9(5):472-477.

Molecular Formula C23H28FN2O5P
Molecular Weight 462.45