1217837-17-6

1217837-17-6 structure

Name: 5-Iodo-A-85380 dihydrochloride
Chemical Name: 3-[(2S)-2-Azetidinylmethoxy]-5-iodopyridine dihydrochloride
CAS Number: 1217837-17-6
Molecular Formula: C₉H₁₃Cl₂IN₂O
Molecular Weight: 363.023
Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
Create Date: 2018-06-04 19:45:17
Modify Date: 2025-08-25 18:18:18
5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR. 5-Iodo-A-85380 dihydrochloride binds to α4β2 nAChRs in rat and human brain with Kds of 12 and 14 pM,respectively[1].

Name	3-[(2S)-2-Azetidinylmethoxy]-5-iodopyridine dihydrochloride
Synonyms	3-[(2S)-Azetidin-2-ylmethoxy]-5-iodopyridine dihydrochloride Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo-, hydrochloride (1:2) 3-[(2S)-2-Azetidinylmethoxy]-5-iodopyridine dihydrochloride MFCD03791315

Description	5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR. 5-Iodo-A-85380 dihydrochloride binds to α4β2 nAChRs in rat and human brain with Kds of 12 and 14 pM,respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
References	[1]. Mukhin AG, et al. 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol Pharmacol. 2000 Mar;57(3):642-9.