111768-16-2
111768-16-2 structure
- Name: Demethoxyfumitremorgin C
- Chemical Name: demethoxyfumitremorgin C
- CAS Number: 111768-16-2
- Molecular Formula: C21H23N3O2
- Molecular Weight: 349.43
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2018-06-05 07:05:36
- Modify Date: 2025-08-20 19:07:52
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Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage[1].
| Name | demethoxyfumitremorgin C |
|---|---|
| Synonyms |
5H,14H-Pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione, 1,2,3,5a,6,11,12,14a-octahydro-12-(2-methyl-1-propen-1-yl)-, (5aS,12S,14aS)-
demethoxyfumitremorgin C (5aS,12S,14aS)-12-(2-Methyl-1-propen-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione |
| Description | Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 617.8±55.0 °C at 760 mmHg |
| Molecular Formula | C21H23N3O2 |
| Molecular Weight | 349.43 |
| Flash Point | 327.4±31.5 °C |
| Exact Mass | 349.179016 |
| LogP | 1.89 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.692 |
| Storage condition | 2-8℃ |
| Hazard Codes | Xi |
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