146961-76-4

146961-76-4 structure

Name: Alatrofloxacin
Chemical Name: Alatrofloxacin
CAS Number: 146961-76-4
Molecular Formula: C₂₆H₂₅F₃N₆O₅
Molecular Weight: 558.509
Catalog: API Synthetic anti-infective drugs Quinolone
Create Date: 2018-07-13 23:39:59
Modify Date: 2024-01-09 11:05:18
Alatrofloxacin, the parenteral prodrug of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity[1].

Name	Alatrofloxacin
Synonyms	7495 Alatrofloxacin L-Alaninamide, L-alanyl-N-[(1R,5S)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]- 7QVV6I50DT L-Alanyl-N-{(1R,5S,6s)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl}-L-alaninamide

Description	Alatrofloxacin, the parenteral prodrug of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
References	[1]. Hall IH, et al. Effects of alatrofloxacin, the parental prodrug of trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes. Biomed Pharmacother. 2003;57(8):359-365.