Alatrofloxacin

Modify Date: 2024-01-09 11:05:18

Alatrofloxacin Structure
Alatrofloxacin structure
Common Name Alatrofloxacin
CAS Number 146961-76-4 Molecular Weight 558.509
Density 1.6±0.1 g/cm3 Boiling Point 863.2±65.0 °C at 760 mmHg
Molecular Formula C26H25F3N6O5 Melting Point N/A
MSDS N/A Flash Point 475.8±34.3 °C

 Use of Alatrofloxacin


Alatrofloxacin, the parenteral prodrug of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity[1].

 Names

Name Alatrofloxacin
Synonym More Synonyms

 Alatrofloxacin Biological Activity

Description Alatrofloxacin, the parenteral prodrug of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity[1].
Related Catalog
References

[1]. Hall IH, et al. Effects of alatrofloxacin, the parental prodrug of trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes. Biomed Pharmacother. 2003;57(8):359-365.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 863.2±65.0 °C at 760 mmHg
Molecular Formula C26H25F3N6O5
Molecular Weight 558.509
Flash Point 475.8±34.3 °C
Exact Mass 558.183838
LogP 0.33
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.673

 Synonyms

7495
Alatrofloxacin
L-Alaninamide, L-alanyl-N-[(1R,5S)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-
7QVV6I50DT
L-Alanyl-N-{(1R,5S,6s)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl}-L-alaninamide
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