1375751-08-8
1375751-08-8 structure
- Name: BMS-955829
- Chemical Name: (4R,5R)-5-(2,5-Difluorophenyl)-4-[5-(phenylethynyl)-3-pyridinyl]-1,3-oxazolidin-2-one
- CAS Number: 1375751-08-8
- Molecular Formula: C22H14F2N2O2
- Molecular Weight: 376.356
- Create Date: 2018-06-05 19:27:34
- Modify Date: 2024-01-28 23:28:11
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A potent, selective, low glutamate fold shift (2.4) mGluR5 positive allosteric modulator with EC50 of 2.6 nM, without inherent mGluR5 agonist activity (EC50>30 uM).
| Name | (4R,5R)-5-(2,5-Difluorophenyl)-4-[5-(phenylethynyl)-3-pyridinyl]-1,3-oxazolidin-2-one |
|---|---|
| Synonyms |
2-Oxazolidinone, 5-(2,5-difluorophenyl)-4-[5-(2-phenylethynyl)-3-pyridinyl]-, (4R,5R)-
MFCD30471079 (4R,5R)-5-(2,5-Difluorophenyl)-4-[5-(phenylethynyl)-3-pyridinyl]-1,3-oxazolidin-2-one BMS-955829 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 589.2±50.0 °C at 760 mmHg |
| Molecular Formula | C22H14F2N2O2 |
| Molecular Weight | 376.356 |
| Flash Point | 310.2±30.1 °C |
| Exact Mass | 376.102325 |
| LogP | 4.53 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.654 |