128802-76-6

128802-76-6 structure

Name: Suc-Ala-Glu-Pro-Phe-pNA
Chemical Name: N-(3-Carboxypropanoyl)-L-alanyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)-L-phenylalaninamide
CAS Number: 128802-76-6
Molecular Formula: C₃₂H₃₈N₆O₁₁
Molecular Weight: 682.678
Catalog: Research Areas Others
Create Date: 2018-07-10 22:25:08
Modify Date: 2024-01-12 10:50:55
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc[1][2].

Name	N-(3-Carboxypropanoyl)-L-alanyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)-L-phenylalaninamide
Synonyms	N-(3-Carboxypropanoyl)-L-alanyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)-L-phenylalaninamide MFCD00238367 L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)- Suc-Ala-Glu-Pro-Phe-pNA

Description	Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc[1][2].
Related Catalog	Research Areas >> Others
References	[1]. Subedi A, et al. Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening. Biochem Biophys Res Commun. 2016 Jun 3;474(3):528-533. [2]. Liu C, et al. Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1. Mol Med Rep. 2017 May;15(5):3210-3214.