948027-43-8

948027-43-8 structure

Name: 3-Pyr-Cytisine
Chemical Name: (1R,9S)-5-(3-Pyridinyl)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one
CAS Number: 948027-43-8
Molecular Formula: C₁₆H₁₇N₃O
Molecular Weight: 267.33
Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
Create Date: 2018-07-18 18:15:49
Modify Date: 2024-01-31 15:30:58
3-Pyr-Cytisine (3-Pyr-Cyt) is a cytisine derivative. 3-Pyr-Cytisine is a very weak α4β2 nAChR partial agonist that has been studied as an antidepressant[1].

Name	(1R,9S)-5-(3-Pyridinyl)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one
Synonyms	(1R,9S)-5-(3-Pyridinyl)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-9-(3-pyridinyl)-, (1R,5S)-

Description	3-Pyr-Cytisine (3-Pyr-Cyt) is a cytisine derivative. 3-Pyr-Cytisine is a very weak α4β2 nAChR partial agonist that has been studied as an antidepressant[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
References	[1]. Igari M, et al. Varenicline and cytisine diminish the dysphoric-like state associated with spontaneous nicotine withdrawal in rats. Neuropsychopharmacology. 2014 Jan;39(2):455-65.