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1946010-79-2

1946010-79-2 structure
1946010-79-2 structure
  • Name: SAR405 R enantiomer
  • Chemical Name: SAR405 R enantiomer
  • CAS Number: 1946010-79-2
  • Molecular Formula: C19H21ClF3N5O2
  • Molecular Weight: 443.850
  • Catalog: Research Areas Cancer
  • Create Date: 2018-01-05 07:33:28
  • Modify Date: 2024-01-08 11:36:31
  • SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is a PIK3C3/Vps34 inhibitor.

Name SAR405 R enantiomer
Synonyms 4H-Pyrimido[1,2-a]pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-, (8R)-
(8R)-9-[(5-Chloro-3-pyridinyl)methyl]-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one
Description SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is a PIK3C3/Vps34 inhibitor.
Related Catalog
References

[1]. Pasquier B. SAR405, a PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. Autophagy. 2015 Apr 3;11(4):725-6.

Density 1.5±0.1 g/cm3
Boiling Point 526.5±60.0 °C at 760 mmHg
Molecular Formula C19H21ClF3N5O2
Molecular Weight 443.850
Flash Point 272.2±32.9 °C
Exact Mass 443.133575
LogP 1.97
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.635
Storage condition 2-8℃