SAR405 R enantiomer

Modify Date: 2024-01-08 11:36:31

SAR405 R enantiomer Structure
SAR405 R enantiomer structure
Common Name SAR405 R enantiomer
CAS Number 1946010-79-2 Molecular Weight 443.850
Density 1.5±0.1 g/cm3 Boiling Point 526.5±60.0 °C at 760 mmHg
Molecular Formula C19H21ClF3N5O2 Melting Point N/A
MSDS N/A Flash Point 272.2±32.9 °C

 Use of SAR405 R enantiomer


SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is a PIK3C3/Vps34 inhibitor.

 Names

Name SAR405 R enantiomer
Synonym More Synonyms

 SAR405 R enantiomer Biological Activity

Description SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is a PIK3C3/Vps34 inhibitor.
Related Catalog
References

[1]. Pasquier B. SAR405, a PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. Autophagy. 2015 Apr 3;11(4):725-6.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 526.5±60.0 °C at 760 mmHg
Molecular Formula C19H21ClF3N5O2
Molecular Weight 443.850
Flash Point 272.2±32.9 °C
Exact Mass 443.133575
LogP 1.97
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.635
Storage condition 2-8℃

 Synonyms

4H-Pyrimido[1,2-a]pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-, (8R)-
(8R)-9-[(5-Chloro-3-pyridinyl)methyl]-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one