1216673-02-7

1216673-02-7 structure

Name: Linalool-d3
Chemical Name: Linalool(1,1,2-D3)
CAS Number: 1216673-02-7
Molecular Formula: C₁₀H₁₅D₃O
Molecular Weight: 157.268
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-04-04 02:02:22
Modify Date: 2024-01-18 07:42:46
Linalool-d3 is the deuterium labeled Linalool[1]. Linalool is natural monoterpene in essential olis of coriander, acts as a competitive antagonist of Nmethyl d-aspartate (NMDA) receptor, with anti-tumor, anti-cardiotoxicity activity[2].Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome[3].

Name	Linalool(1,1,2-D3)
Synonyms	3,7-Dimethyl(1,1,2-H)-1,6-octadien-3-ol Linalool(1,1,2-D3) (±)-Linalool-d3 (vinyl-d3) 3,7-Dimethyl(1,1,2-H)octa-1,6-dien-3-ol 1,6-Octadien-1,1,2-d-3-ol, 3,7-dimethyl-

Description	Linalool-d3 is the deuterium labeled Linalool[1]. Linalool is natural monoterpene in essential olis of coriander, acts as a competitive antagonist of Nmethyl d-aspartate (NMDA) receptor, with anti-tumor, anti-cardiotoxicity activity[2].Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome[3].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Oner Z1, et al. The protective and therapeutic effects of linalool against doxorubicin-induced cardiotoxicity in Wistar albino rats. Hum Exp Toxicol. 2019 Apr 12:960327119842634. [3]. Jun HJ, et al. Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome. J Lipid Res. 2014 Jun55(6):1098-110.