DC Chemicals Limited
China
Product Name: (+)-Muscarine (chloride)
Price: $550.0/100mg $1100.0/250mg $2200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (+)-MUSCARINE CHLORIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

2303-35-7

2303-35-7 structure

2303-35-7 structure

Name: (+)-Muscarine (chloride)
Chemical Name: (+)-muscarine chloride
CAS Number: 2303-35-7
Molecular Formula: C₉H₂₀ClNO₂
Molecular Weight: 209.71400
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2018-03-13 23:01:04
Modify Date: 2024-01-05 19:13:18
Muscarine ((+)-Muscarine) chloride is a toxin that can stimulate the parasympathetic nervous system. Muscarine is a prototype muscarinic acetylcholine receptor agonist[1][2].

Name	(+)-muscarine chloride
Synonyms	muscarine chloride muscarine ((2S)-4c-hydroxy-5t-methyl-(2rH)-tetrahydro-furfuryl)-trimethyl-ammonium, chloride ((2S)-4c-Hydroxy-5t-methyl-(2rH)-tetrahydro-furfuryl)-trimethyl-ammonium, Chlorid

Description	Muscarine ((+)-Muscarine) chloride is a toxin that can stimulate the parasympathetic nervous system. Muscarine is a prototype muscarinic acetylcholine receptor agonist[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
In Vitro	Muscarine administration (100 µM) induces an intracellular calcium signal amplitude similar to the one triggered by 10 µM ACh[1]. Muscarine (1-30 μM) produces a dose-dependent hyperpolarization in a sub-population of the NRM cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons[2].
References	[1]. Beatrice Mihaela Radu, et al. All muscarinic acetylcholine receptors (M 1-M 5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017 Jul 11;7(1):5083. [2]. Z Z Pan, et al. Muscarine hyperpolarizes a subpopulation of neurons by activating an M2 muscarinic receptor in rat nucleus raphe magnus in vitro. J Neurosci. 1994 Mar;14(3 Pt 1):1332-8.

Molecular Formula	C₉H₂₀ClNO₂
Molecular Weight	209.71400
Exact Mass	209.11800
PSA	29.46000
LogP	1.03290

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300-H310-H330
Precautionary Statements	P260-P264-P280-P284-P302 + P350-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
RIDADR	UN 2811 6.1 / PGII
RTECS	QG3500000