Name | N-BOC-Diethanolamine |
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Synonyms |
MFCD01862953
N-Boc-diethanolamine tert-Butyl bis(2-hydroxyethyl)carbamate TERT-BUTYL N,N-BIS(2-HYDROXYETHYL)CARBAMATE |
Description | N-Boc-diethanolamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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Related Catalog | |
Target |
Cleavable |
In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
References |
Density | 1.085 |
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Boiling Point | 324.2ºC at 760 mmHg |
Molecular Formula | C9H19NO4 |
Molecular Weight | 205.25100 |
Flash Point | 149.9ºC |
Exact Mass | 205.13100 |
PSA | 70.00000 |
LogP | 0.20810 |
Appearance | Liquid or Oil | Colorless |
Vapour Pressure | 1.95E-05mmHg at 25°C |
Index of Refraction | 1.46 |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2924199090 |
~98% 103898-11-9 |
Literature: Donaldson, Susan F.; Bergmeier, Stephen C.; Hines, Jennifer V.; Gerdeman, Melinda S. Nucleosides, Nucleotides and Nucleic Acids, 2002 , vol. 21, # 2 p. 111 - 123 |
~% 103898-11-9 |
Literature: US4987130 A1, ; |
Precursor 3 | |
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DownStream 2 | |
HS Code | 2924199090 |
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Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |