Name | (2S)-2-[[(3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydroisochromene-7-carbonyl]amino]-3-phenylpropanoic acid |
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Synonyms |
OCHRATOXIN B
Ochratoxin B solution ochratoxin A N-{[(3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromen-7-yl]-carbonyl}-L-phenylalanine N-{[(3R)-8-Hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromen-7-yl]carbonyl}-L-phenylalanine Alanine,N-((8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenyl-,(-) N-{[(3R)-8-hydroxy-3-methyl-1-oxo-7-isochromanyl]carbonyl}-3-phenyl-L-alanine (R)-N-[(3,4-Dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carboxyl]phenylalanine L-Phenylalanine, N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]- L-Phenylalanine,N-((3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl)-,(R) Ochratoxin B(OTB) |
Description | Ochratoxin B, a secondary metabolite of Aspergillus ochraceus, is the nonchlorinated analogue of the mycotoxin Ochratoxin A. Ochratoxin B has been shown to reduce the toxic effects of Ochratoxin A, and it is one of the most potent renal carcinogens in rodents[1][2]. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 632.4±55.0 °C at 760 mmHg |
Melting Point | 221ºC |
Molecular Formula | C20H19NO6 |
Molecular Weight | 369.368 |
Flash Point | 336.2±31.5 °C |
Exact Mass | 369.121246 |
PSA | 112.93000 |
LogP | 3.06 |
Vapour Pressure | 0.0±2.0 mmHg at 25°C |
Index of Refraction | 1.623 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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Symbol |
GHS02, GHS07 |
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Signal Word | Danger |
Hazard Statements | H225-H302-H312-H319-H332 |
Precautionary Statements | P210-P280-P305 + P351 + P338 |
Hazard Codes | Xn,T,F |
Risk Phrases | 22-36/37/38-65-48/23/24/25-36/38-11-46-45 |
Safety Phrases | 26-36-45-16-53 |
RIDADR | UN 3462 6.1/PG 3 |
WGK Germany | 3 |
RTECS | AY6825000 |
Packaging Group | I |
Hazard Class | 6.1(a) |
HS Code | 39229000 |
~% 4825-86-9 |
Literature: Gillman, Ivan G.; Yezek, Jennifer M.; Manderville, Richard A. Chemical Communications, 1998 , # 6 p. 647 - 648 |
~% 4825-86-9 |
Literature: Brow, Mark E.; Dai, Jian; Park, Gyungse; Wright, Marcus W.; Gillman, Ivan G.; Manderville, Richard A. Photochemistry and Photobiology, 2002 , vol. 76, # 6 p. 649 - 656 |
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Detail
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Literature: Hadjeba-Medjdoub, Kheira; Tozlovanu, Mariana; Pfohl-Leszkowicz, Annie; Frenette, Christine; Paugh, Robert J.; Manderville, Richard A. Chemical Research in Toxicology, 2012 , vol. 25, # 1 p. 181 - 190 |