- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Heparin lithium salt
- Price: ￥1878.0/5g ￥568.0/1g
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Heparin Lithium salt
- Price: $100.0/100mg $200.0/250mg $400.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Heparin, lithium salt
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: HEPARIN LITHIUM SALT
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Lithium heparin
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
9045-22-1
9045-22-1 structure
- Name: Heparin lithium salt
- Chemical Name: Heparin lithium salt
- CAS Number: 9045-22-1
- Molecular Formula: (C14H25NO20S3)n.xLi
- Molecular Weight: 148.159
- Catalog: Biochemical Carbohydrate Polysaccharide
- Create Date: 2018-08-28 17:29:07
- Modify Date: 2024-01-04 08:29:31
-
Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII).
| Name | Heparin lithium salt |
|---|---|
| Synonyms |
(E)-3-Phenylprop-2-enoic acid
Propenoic acid, 3-phenyl-, (trans)- MFCD00131308 Cinnamic acid (2E)-3-Phenylacrylic acid trans-Cinnamic Acid QV1U1R &&Trans or E Form 2-Propenoic acid, 3-phenyl-, (2E)- 4-09-00-02002 (Beilstein Handbook Reference) trans-b-Carboxystyrene |
| Description | Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII). |
|---|---|
| Related Catalog | |
| Target |
Antithrombin III[1] |
| In Vitro | Heparin is a potent anticoagulant drug based on its ability to accelerate the rate at which antithrombin inhibits serine proteases in the blood coagulation cascade. Heparin interactes most tightly with peptides containing a complementary binding site of high positive charge density. Heparin resembles DNA as both are highly charged linear polymers that behave as polyelectrolytes. Heparin is believed to function as an anticoagulant primarily through its interaction with AT III by enhancing AT-III-mediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin binds to AT III and thrombin in a ternary complex, increasing the bimolecular rate constant for the inhibition of thrombin by a factor of 2000. Heparin is principally located in the granules of tissue mast cells that are closely associated with the immune response. Heparin makes numerous contacts with both FGF-2 and FGFR-1 stabilizing FGF–FGFR binding. Heparin also makes contacts with the FGFR-1 of the adjacent FGF–FGFR complex, thus seeming to promote FGFR dimerization[1]. |
| References |
[1]. Capila I, et al. Heparin-protein interactions. Angew Chem Int Ed Engl. 2002 Feb 1;41(3):391-412. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 265.0±0.0 °C at 760 mmHg |
| Molecular Formula | (C14H25NO20S3)n.xLi |
| Molecular Weight | 148.159 |
| Flash Point | 189.5±9.6 °C |
| Exact Mass | 148.052429 |
| LogP | 2.41 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.616 |
| Storage condition | +15C to +30C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 22-24/25-36-26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | MI0700000 |
| HS Code | 29319090 |