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9004-64-2

9004-64-2 structure
9004-64-2 structure
  • Name: Hydroxypropyl Cellulose
  • Chemical Name: Hydroxypropyl cellulose
  • CAS Number: 9004-64-2
  • Molecular Formula: C36H70O19
  • Molecular Weight: 806.930
  • Catalog: Biochemical Carbohydrate Polysaccharide
  • Create Date: 2018-07-29 10:15:19
  • Modify Date: 2024-01-02 18:24:09
  • Hydroxypropyl Cellulose is somewhat amphiphilic in character and is a surfactant. Hydroxypropyl Cellulose can be used as a pharmaceutical excipient, such as coating agent, emulsifier, suspension, tablet, thickener, viscosifier. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

Name Hydroxypropyl cellulose
Synonyms β-D-Glucopyranoside, 2-hydroxypropyl 2,3,6-tris-O-(2-hydroxypropyl)-4-O-[2,3,4,6-tetrakis-O-(2-hydroxypropyl)-α-D-glucopyranosyl]-
Klucel
MFCD00132688
2-Hydroxypropyl 2,3,6-tris-O-(2-hydroxypropyl)-4-O-[2,3,4,6-tetrakis-O-(2-hydroxypropyl)-α-D-glucopyranosyl]-β-D-glucopyranoside
Description Hydroxypropyl Cellulose is somewhat amphiphilic in character and is a surfactant. Hydroxypropyl Cellulose can be used as a pharmaceutical excipient, such as coating agent, emulsifier, suspension, tablet, thickener, viscosifier. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog
References

[1]. Werbowyj R S, et al. Liquid crystalline structure in aqueous hydroxypropyl cellulose solutions[J]. Molecular Crystals and Liquid Crystals, 1976, 34(4): 97-103.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  

Density 1.3±0.1 g/cm3
Boiling Point 891.2±65.0 °C at 760 mmHg
Molecular Formula C36H70O19
Molecular Weight 806.930
Flash Point 492.8±34.3 °C
Exact Mass 806.451111
LogP -1.24
Appearance powder | White to light cream
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.532
Stability Stable. Incompatible with strong oxidizing agents. Combustible.
Water Solubility polar oganic solvents: soluble
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes S24/S25
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS NF9050000