8009-03-8

8009-03-8 structure

Name: Petrolatum
Chemical Name: Vaseline petroleum jelly
CAS Number: 8009-03-8
Molecular Formula: C₈₆H₁₄₂
Molecular Weight:
Catalog: Food additive Defoamer
Create Date: 2019-02-17 19:18:21
Modify Date: 2024-01-02 11:09:02
Petrolatum (white) is an ointment vehicle for many drugs, due to its low skin irritation. Petrolatum (white) can be used as an excipient, such as ointment base, lubricant, adhesive, viscous agent, excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

Name	Vaseline petroleum jelly
Synonyms	MFCD00147839 EINECS 232-373-2

Description	Petrolatum (white) is an ointment vehicle for many drugs, due to its low skin irritation. Petrolatum (white) can be used as an excipient, such as ointment base, lubricant, adhesive, viscous agent, excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Ishii H, et al. Why does a hydrophilic drug permeate skin, although it is not soluble in white petrolatum?[J]. Drug development and industrial pharmacy, 2009, 35(11): 1356-1363. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Density	0.84
Boiling Point	322 °C
Melting Point	70-80 °C ((ASTM D 127))
Molecular Formula	C₈₆H₁₄₂
Flash Point	198 °C
Appearance	extra-low viscosity \| white
Index of Refraction	n20/D 1.45
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	T
Risk Phrases	R45
Safety Phrases	S53;S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	RV0350000