63968-82-1

63968-82-1 structure

Name: Kassinin
Chemical Name: Kassinin
CAS Number: 63968-82-1
Molecular Formula: C₅₉H₉₅N₁₅O₁₈S
Molecular Weight: 1335.525
Catalog: Peptides
Create Date: 2018-02-25 08:00:00
Modify Date: 2024-01-11 16:44:36
Kassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides. It is secreted as a defense response, and is involved in neuropeptide signalling.

Name	Kassinin
Synonyms	L-Methioninamide, L-α-aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-α-aspartyl-L-α-glutamyl-L-phenylalanyl-L-valylglycyl-L-leucyl- Asp-Val-Pro-Lys-Ser-Asp-Gln-Phe-Val-Gly-Leu-Met-NH2 Kassinin L-α-Aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-α-aspartyl-L-α-glutamyl-L-phenylalanyl-L-valylglycyl-L-leucyl-L-methioninamide

Description	Kassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides. It is secreted as a defense response, and is involved in neuropeptide signalling.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Natural Products >> Others Peptides Research Areas >> Neurological Disease
In Vitro	Amino acid composition and sequence of Kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis. Methanol extracts of the skin of the African amphibian Kassina senegalensis contain a dodecapeptide, Kassinin, belonging to the family of tachykinins or physalaemin-like peptides. Kassinin, like all other natural tachykinins, possesses the characteristic C-terminal tripeptide Gly-Leu-Met-NH2 and a phenylalanine residue in position 5 from the C-terminus. The amino acid sequence in the N-moiety of the molecule differs sharply from that of the other tachykinins[1].
References	[1]. Anastasi A, et al. Amino acid composition and sequence of kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis. Experientia. 1977 Jul 15;33(7):857-8.