9000-81-1

9000-81-1 structure

Name: Native Electrophorus electricus (electric eel) Acetylcholinesterase
Chemical Name: Acetylcholinesterase
CAS Number: 9000-81-1
Molecular Formula: C₃₁H₂₇NO₄
Molecular Weight: 477.550
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2018-02-05 08:00:00
Modify Date: 2024-01-01 23:22:51
Acetylcholinesterase (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses, and is often used in biochemical research. Acetylcholinesterase catalyzes the breakdown or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetate and choline. Acetylcholinesterase's main role is to terminate neuronal transmission and signaling between synapses to prevent ACh spread and activation of nearby receptors[1].

Name	Acetylcholinesterase
Synonyms	Acetylcholine esterase Acetylcholinesterases AcCholE True cholinesterase 5-Benzyl 3-ethyl 2-methyl-6-phenyl-4-(phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate Acetylcholine hydrolase Acetylcholine acetylhydrolase Choline esterase 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-methyl-6-phenyl-4-(2-phenylethynyl)-, 3-ethyl 5-(phenylmethyl) ester Acetyl beta-methylcholinesterase Cholinesterase Acetyl choline esterase MFCD00081268 Acetylcholinesterase (AChE) EINECS 232-559-3 Cholinesterase I Acetylthiocholinesterase E.C. 3.1.1.7 5-Benzyl 3-ethyl 2-methyl-6-phenyl-4-(phenylethynyl)-1,4-dihydro-3,5-pyridinedicarboxylate Native Electrophorus electricus (electric eel) Acetylcholinesterase

Description	Acetylcholinesterase (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses, and is often used in biochemical research. Acetylcholinesterase catalyzes the breakdown or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetate and choline. Acetylcholinesterase's main role is to terminate neuronal transmission and signaling between synapses to prevent ACh spread and activation of nearby receptors[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Israel Silman, et al. Acetylcholinesterase: how is structure related to function? Chem Biol Interact. 2008 Sep 25;175(1-3):3-10.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport