7720-39-0

7720-39-0 structure

Name: 2-Aminoimidazole
Chemical Name: 1H-Imidazol-2-amine
CAS Number: 7720-39-0
Molecular Formula: C₃H₅N₃
Molecular Weight: 83.092
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-03-18 08:00:00
Modify Date: 2024-01-02 08:20:36
2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM[1][2][3].

Name	1H-Imidazol-2-amine
Synonyms	N-imidazolylamine EINECS 231-751-4 1H-Imidazol-2-amine MFCD00792530 2-aminoimidazole

Description	2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Immunology/Inflammation >> Arginase Signaling Pathways >> Anti-infection >> Bacterial
Target	bacteria[1] Ki: 3.6 mM (human arginase I)[3]
References	[1]. Thompson RJ, et, al. Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-Aminoimidazole-based antibiofilm agent. Biochemistry. 2012 Dec 11;51(49):9776-8. [2]. Jacobs L, et, al. 2-Aminoimidazoles as potent inhibitors of contaminating brewery biofilms. Biofouling. 2021 Feb 11;1-17. [3]. Ilies M, et, al. 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. J Med Chem. 2010 May 27;53(10):4266-76.

42383-61-9

~99%

7720-39-0

1450-93-7

~79%

7720-39-0

Literature: Voegel; Altorfer; Benner Helvetica Chimica Acta, 1993 , vol. 76, # 5 p. 2061 - 2069

7647-01-0

93937-81-6

7720-39-0

156-43-4

Literature: Journal of the Society of Dyers and Colourists, vol. 38, p. 271 Chem. Zentralbl., , vol. 94, # I p. 844

7647-01-0

108106-91-8

7720-39-0

121-57-3

Literature: Journal of the Society of Dyers and Colourists, vol. 38, p. 270 Chem. Zentralbl., , vol. 94, # I p. 844

7647-01-0

93937-76-9

7720-39-0

106-40-1

Detail

Literature: Journal of the Chemical Society, , vol. 115, p. 250

7647-01-0

34938-48-2

7720-39-0

7664-41-7

Detail

Literature: Journal of the Chemical Society, , vol. 117, p. 1430

7647-01-0

34938-47-1

7720-39-0

113-00-8

Detail

Literature: Journal of the Chemical Society, , vol. 115, p. 250

HS Code	2933290090
Summary	2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%