849727-81-7

849727-81-7 structure

Name: AMPK activator D942
Chemical Name: 5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl]furan-2-carboxylic acid
CAS Number: 849727-81-7
Molecular Formula: C₂₂H₂₁FO₄
Molecular Weight: 368.398
Create Date: 2017-10-25 12:05:35
Modify Date: 2024-01-10 18:37:56
D942 is a cell penetrant AMPK activator and partially inhibits the mitochondrial complex I. In multiple myeloma cells, D942 inhibits cell growth[1].

Name	5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl]furan-2-carboxylic acid
Synonyms	AMPK Activator 5-(3-{4-[2-(4-Fluorophenyl)ethoxy]phenyl}propyl)-2-furoic acid IN1531 2-Furancarboxylic acid,5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl] D942 2-Furancarboxylic acid, 5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl]- 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid

Description	D942 is a cell penetrant AMPK activator and partially inhibits the mitochondrial complex I. In multiple myeloma cells, D942 inhibits cell growth[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> AMPK
References	[1]. Baumann P, et al. Activation of adenosine monophosphate activated protein kinase inhibits growth of multiple myeloma cells. Exp Cell Res. 2007 Oct 1;313(16):3592-603.