107596-30-5

107596-30-5 structure

Name: S-(+)-Mecamylamine hydrochloride
Chemical Name: S-(+)-Mecamylamine Hydrochloride
CAS Number: 107596-30-5
Molecular Formula: C₁₁H₂₂ClN
Molecular Weight: 203.75200
Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
Create Date: 2018-06-14 10:00:48
Modify Date: 2024-01-10 15:54:14
S-(+)-Mecamylamine (hydrochloride) is a neuronal nicotinic receptor modulator with antidepressant activity.

Name	S-(+)-Mecamylamine Hydrochloride
Synonyms	(1S,3S,4R)-N,2,2,3-tetramethylbicyclo[2.2.1]heptan-3-amine,hydrochloride

Description	S-(+)-Mecamylamine (hydrochloride) is a neuronal nicotinic receptor modulator with antidepressant activity.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
References	[1]. Lippiello PM, Beaver JS, Gatto GJ, et al. TC-5214 (S-(+)-mecamylamine): a neuronal nicotinic receptor modulator with antidepressant activity. CNS Neurosci Ther. 2008;14(4):266-277. [2]. Vieta E, Thase ME, Naber D, et al. Efficacy and tolerability of flexibly-dosed adjunct TC-5214 (dexmecamylamine) in patients with major depressive disorder and inadequate response to prior antidepressant. Eur Neuropsychopharmacol. 2014;24(4):564-574.