79864-95-2

79864-95-2 structure

Name: Butanedioic acid-13C2
Chemical Name: <1,4-13C2>-succinic acid
CAS Number: 79864-95-2
Molecular Formula: C₄H₆O₄
Molecular Weight: 120.07300
Catalog: Research Areas Neurological Disease
Create Date: 2018-03-14 08:00:00
Modify Date: 2024-01-06 12:22:31
Butanedioic acid-13C2 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].

Name	<1,4-13C2>-succinic acid
Synonyms	MFCD00083910 Asuccin-13C2 Butanedioic Acid-13C2 1,4-{13C}-succinic acid Amber Acid-13C2 Yantar-antitox-13C2 Succinic acid-1,4-13C2 Katasuccin-13C2 Wormwood Acid-13C2 Butanedioic acid-1,4-13C2 Dihydrofumaric Acid-13C2 Succinic Acid-1,4-13C3 Succinic Acid (1,4-13C2, 99%)

Description	Butanedioic acid-13C2 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
Related Catalog	Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Zhang YJ, et al. Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM). J Zhejiang Univ Sci B. 2012 Feb;13(2):103-10. [3]. A T JOHNS, et al. The production of propionic acid by decarboxylation of succinic acid in a bacterial fermentation. Biochem J. 194842(1):ii. [4]. Si Wei Chen, Anxiolytic-like effect of succinic acid in mice. Life Sci. 2003 Nov 773(25):3257-64.

Density	1.409g/cm3
Boiling Point	235ºC
Melting Point	187-190ºC(lit.)
Molecular Formula	C₄H₆O₄
Molecular Weight	120.07300
Exact Mass	120.03300
PSA	74.60000
Index of Refraction	1.478

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38-41
Safety Phrases	26-36
RIDADR	NONH for all modes of transport

79341-57-4

~98%

79864-95-2

Literature: Vishwakarma, Ram A.; Balachandran, Salara; Alanine, Alex I. D.; Stamford, N. Patrick J.; Kiuchi, Fumiyuki Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 23 p. 2893 - 2900

106-93-4

79864-95-2

Literature: Kushner; Weinhouse Journal of the American Chemical Society, 1949 , vol. 71, p. 3558

25909-68-6

107-06-2

79864-95-2

Literature: Ashworth, Doreen M.; Robinson, John A.; Turner, David L. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1719 - 1728

Precursor 4
79341-57-4 106-93-4 25909-68-6 107-06-2
DownStream 1
67519-25-9

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