877384-16-2
877384-16-2 structure
- Name: BENZYL ((1R,2S)-1-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)-1-HYDROXYPROPAN-2-YL)CARBAMATE
- Chemical Name: benzyl N-[(1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-1-hydroxypropan-2-yl]carbamate
- CAS Number: 877384-16-2
- Molecular Formula: C19H17F6NO3
- Molecular Weight: 421.334
- Create Date: 2018-06-20 09:43:14
- Modify Date: 2024-02-01 22:17:06
| Name | benzyl N-[(1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-1-hydroxypropan-2-yl]carbamate |
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| Synonyms |
Carbamic acid, N-[(1S,2R)-2-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-1-methylethyl]-, phenylmethyl ester
[(1S,2R)-2-[3,5-Bis(trifluoromethyl)phenyl]-2-hydroxy-1-methylethyl]carbamic acid phenylmethyl ester Benzyl {(1R,2S)-1-[3,5-bis(trifluoromethyl)phenyl]-1-hydroxy-2-propanyl}carbamate benzyl (1R,2S)-1-(3,5-bis(trifluoromethyl)phenyl)-1-hydroxypropan-2-ylcarbamate (1R,2S)-1-(3',5'-bis(trifluoromethyl)phenyl)-2-benzyloxycarbonylamino-1-propanol Anacetrapib Intermediate 1 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 442.8±45.0 °C at 760 mmHg |
| Molecular Formula | C19H17F6NO3 |
| Molecular Weight | 421.334 |
| Flash Point | 221.6±28.7 °C |
| Exact Mass | 421.111267 |
| PSA | 58.56000 |
| LogP | 4.71 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.498 |
| Hazard Codes | Xi |
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877384-16-2 |
| Literature: MERCK and CO., INC. Patent: WO2006/14357 A1, 2006 ; Location in patent: Page/Page column 51-52 ; |
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877384-16-2 |
| Literature: Smith, Cameron J.; Ali, Amjad; Hammond, Milton L.; Li, Hong; Lu, Zhijian; Napolitano, Joann; Taylor, Gayle E.; Thompson, Christopher F.; Anderson, Matt S.; Chen, Ying; Eveland, Suzanne S.; Guo, Qiu; Hyland, Sheryl A.; Milot, Denise P.; Sparrow, Carl P.; Wright, Samuel D.; Cumiskey, Anne-Marie; Latham, Melanie; Peterson, Laurence B.; Rosa, Ray; Pivnichny, James V.; Tong, Xinchun; Xu, Suoyu S.; Sinclair, Peter J. Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4880 - 4895 |
| Precursor 1 | |
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| DownStream 1 | |
