875444-08-9

875444-08-9 structure

Name: (4R,5S)-5-(3,5-bis(trifluoroMethyl)phenyl)-4-Methyloxazolidin-2-one
Chemical Name: (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one
CAS Number: 875444-08-9
Molecular Formula: C₁₂H₉F₆NO₂
Molecular Weight: 313.196
Create Date: 2018-12-26 08:23:03
Modify Date: 2024-01-03 19:15:19

Name	(4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one
Synonyms	(4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-1,3-oxazolidin-2-one 2-Oxazolidinone, 5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-, (4S,5R)- 2-Oxazolidinone,5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-,(4S,5R) (4S,5R)-5-(3,5-bis-trifluoromethyl-phenyl)-4-methyl-oxazolidin-2-one (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one (4R,5S)-5-(3,5-bis(trifluoroMethyl)phenyl)-4-Methyloxazolidin-2-one Anacetrapib Intermediate 2

Density	1.4±0.1 g/cm3
Boiling Point	329.5±42.0 °C at 760 mmHg
Molecular Formula	C₁₂H₉F₆NO₂
Molecular Weight	313.196
Flash Point	153.1±27.9 °C
Exact Mass	313.053741
PSA	38.33000
LogP	3.31
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.433

871917-79-2

~98%

875444-08-9

Literature: MERCK and CO., INC. Patent: WO2007/81569 A2, 2007 ; Location in patent: Page/Page column 34-35 ;

877384-16-2

875444-08-9

Literature: MERCK and CO., INC. Patent: WO2006/14357 A1, 2006 ; Location in patent: Page/Page column 51-52 ;

1182350-90-8

875444-08-9

Literature: AMIRA PHARMACEUTICALS, INC. Patent: WO2009/108720 A2, 2009 ; Location in patent: Page/Page column 132 ; WO 2009/108720 A2

1402799-12-5

1402799-13-6

1152029-16-7

1402799-11-4

32315-10-9

Detail

Literature: MERCK and CO., INC. Patent: WO2007/81571 A2, 2007 ; Location in patent: Page/Page column 41 ;

17352-25-9

875444-08-9

Literature: Ogawa, Takanori; Kumagai, Naoya; Shibasaki, Masakatsu Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6196 - 6201 Angew. Chem., 2013 , vol. 125, # 24 p. 6316 - 6321

Precursor 5
877384-16-2 1182350-90-8 1152029-16-7 32315-10-9
17352-25-9
DownStream 1
875446-37-0

56-41-7	108-65-6
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