491831-49-3
491831-49-3 structure
- Name: TB-03
- Chemical Name: (3R)-4-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-4-oxo-3-[[4-(phosphonomethyl)phenyl]methyl]butanoic acid
- CAS Number: 491831-49-3
- Molecular Formula: C36H45N4O9P
- Molecular Weight: 708.73800
- Create Date: 2017-06-18 01:17:15
- Modify Date: 2025-08-25 19:17:20
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A small molecule Grb2 SH2 domain binding antagonist that synergistically enhances inhibition of K562 leukemia cell proliferation by imatinib (CI=0.774).
| Name | (3R)-4-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-4-oxo-3-[[4-(phosphonomethyl)phenyl]methyl]butanoic acid |
|---|---|
| Synonyms | TB-03 |
| Molecular Formula | C36H45N4O9P |
|---|---|
| Molecular Weight | 708.73800 |
| Exact Mass | 708.29200 |
| PSA | 235.03000 |
| LogP | 4.95220 |