7423-96-3

7423-96-3 structure

Name: 3-fluoro-L-tyrosine
Chemical Name: 3-Fluoro-L-tyrosine
CAS Number: 7423-96-3
Molecular Formula: C₉H₁₀FNO₃
Molecular Weight: 199.18
Catalog: Biochemical Amino acids and their derivatives Tyrosine derivatives
Create Date: 2018-08-19 18:36:13
Modify Date: 2025-08-20 11:42:48
3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association[1][2].

Name	3-Fluoro-L-tyrosine
Synonyms	(2S)-2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid MFCD00002607

Description	3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Iron A, et al. Action of the phosphonic analogue of tyrosine and of other tyrosine derivatives on rat liver tyrosine aminotransferase. Amino Acids. 1993 Feb;5(1):33-7. [2]. Phillips RS, et al. Effects of tyrosine ring fluorination on rates and equilibria of formation of intermediates in the reactions of carbon-carbon lyases. Eur J Biochem. 1997 Mar 1;244(2):658-63.

Melting Point	260-261°C
Molecular Formula	C₉H₁₀FNO₃
Molecular Weight	199.18
Flash Point	>110°C
Exact Mass	199.06400
PSA	83.55000
LogP	1.18600
Index of Refraction	-9 ° (C=1, 1mol/L HCl)
Stability	Stable. Incompatible with strong oxidizing agents, strong reducing agents.

56-45-1

367-12-4

~75%

7423-96-3

Literature: Walker, T. E.; Matheny, C.; Storm, C. B.; Hayden, H. Journal of Organic Chemistry, 1986 , vol. 51, # 8 p. 1175 - 1179

367-12-4

127-17-3

7423-96-3

Literature: Journal of the American Chemical Society, , vol. 120, # 28 p. 6851 - 6858

367-12-4

113-24-6

~83%

7423-96-3

35068-04-3

7423-96-3

Literature: Journal of Fluorine Chemistry, , vol. 37, p. 267 - 278

35068-04-3

7423-96-3

78709-81-6

Literature: Journal of Fluorine Chemistry, , vol. 37, p. 267 - 278

60-18-4

7423-96-3

Literature: Journal of Fluorine Chemistry, , vol. 37, p. 267 - 278

3417-91-2

7423-96-3

Literature: Journal of Fluorine Chemistry, , vol. 37, p. 267 - 278

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%