73815-11-9
73815-11-9 structure
- Name: CIMOXATONE
- Chemical Name: 3-[[4-[5-(methoxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]benzonitrile
- CAS Number: 73815-11-9
- Molecular Formula: C19H18N2O4
- Molecular Weight: 338.35700
- Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
- Create Date: 2018-06-26 08:03:05
- Modify Date: 2024-01-11 09:24:46
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Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A)[1].
| Name | 3-[[4-[5-(methoxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]benzonitrile |
|---|---|
| Synonyms |
Cimoxatone
Cimoxatone (INN) Cimoxatonum [INN-Latin] EINECS 277-613-7 Cimoxatono [INN-Spanish] |
| Description | Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A)[1]. |
|---|---|
| Related Catalog | |
| Target |
MAO-A |
| In Vivo | Cimoxatone (20 mg/kg; p.o.) 增强 5-HT (1 mg/kg; s.c.) 对大鼠的厌食作用[1]。 Animal Model: 250-300 g, Adult male Wistar rats[1] Dosage: 20 mg/kg Administration: P.o. Result: Significiantly reduced sucrose intake induced by 1 mg/kg 5-HT or its vehicle injected 2 and 24 h later, significantly enhanced the anorectic action of 5-HT at 2 h but not at 24 h. |
| Density | 1.29g/cm3 |
|---|---|
| Boiling Point | 509.3ºC at 760 mmHg |
| Molecular Formula | C19H18N2O4 |
| Molecular Weight | 338.35700 |
| Flash Point | 261.8ºC |
| Exact Mass | 338.12700 |
| PSA | 71.79000 |
| LogP | 3.17388 |
| Index of Refraction | 1.613 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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