CDK9-IN-10

Names

[ CAS No. ]:
3542-63-0

[ Name ]:
CDK9-IN-10

[Synonym ]:
7-Benzyloxy-5,8-dihydroxy-2-phenyl-chromen-4-on
7-Benzyloxy-5,8-dihydroxy-flavon

Biological Activity

[Description]:

CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

CDK9


[References]

[1]. Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H16O5

[ Molecular Weight ]:
360.35900

[ Exact Mass ]:
360.10000

[ PSA ]:
79.90000

[ LogP ]:
4.45020

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2914509090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Related Compounds