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CDK9-IN-12

Names

[ CAS No. ]:
1942843-54-0

[ Name ]:
CDK9-IN-12

Biological Activity

[Description]:

CDK9-IN-12 displays the optimal CDK9 inhibitory activity with an IC50 value of 5.41 nM.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

CDK9/cyclinT1:5.41 nM (IC50)


[References]

[1]. Han X, et al. Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia. J Med Chem. 2021 Oct 14;64(19):14647-14663.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H19ClN4O

[ Molecular Weight ]:
378.85

Related Compounds