EGFR-IN-54

Names

[ Name ]:
EGFR-IN-54

Biological Activity

[Description]:

EGFR-IN-54 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 1.623 µM. EGFR-IN-54 shows cytotoxic activity against cancer cell lines[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

[Target]

EGFR:1.623 μM (IC50)

[References]

[1]. Abbas SY, et al. Synthesis and anticancer activity of thiourea derivatives bearing a benzodioxole moiety with EGFR inhibitory activity, apoptosis assay and molecular docking study. Eur J Med Chem. 2020 Jul 15;198:112363.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₄N₄O₄S₃

[ Molecular Weight ]:
434.51

Related Compounds

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