<Suppliers Price>

EGFR-IN-28

Names

[ CAS No. ]:
2754392-31-7

[ Name ]:
EGFR-IN-28

Biological Activity

[Description]:

EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> JAK/STAT Signaling >> EGFR
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

[Target]

EGFR


[In Vitro]

EGFR-IN-28 inhibits Δ19Del, L858R, Δ19Del/T790M, L858R/T790M, Δ19Del/T790M/C797S, L858R/T790M/C797S (all IC50s≤50nM)[1].

[References]

[1]. Xianming Deng, et al. EGFR inhibitor, preparation method and application thereof. WO2021238827A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H39BrN10O3S

[ Molecular Weight ]:
711.68

Related Compounds