SM-6586
Names
Biological Activity
[Description]:
SM-6586 is a calcium channel antagonist and inhibitor of Na+/H+ and Na+/Ca2+ exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension.
[Related Catalog]:
[In Vivo]
In SM-6586-treated spontaneously hypertensive rats, the survival rate after bilateral common carotid artery ligation is higher, the brain water content is lower, and the ATP level is higher and lactate level. In focal ischemia models, the SM-treated group shows a reduction of T1 relaxation time. The brain water content is significantly decreased in the SM-treated group[1].
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.31g/cm3
[ Boiling Point ]:
561.3ºC at 760mmHg
[ Molecular Formula ]:
C26H27N5O5
[ Molecular Weight ]:
489.52300
[ Flash Point ]:
293.3ºC
[ Exact Mass ]:
489.20100
[ PSA ]:
129.54000
[ LogP ]:
3.63880
[ Vapour Pressure ]:
1.25E-12mmHg at 25°C
[ Index of Refraction ]:
1.635
[ Storage condition ]:
2-8℃