Vitamin E

Names

[ Name ]:
Vitamin E

[Synonym ]:
(2R)-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol
DL-TOCOPHEROL
dl-alpha-Tocopherol(E)
ecyl)
ephanyl
alpha-Tocopherol
(±)-α-Tocopherol
(2R)-2,5,7,8-Tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]chroman-6-ol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-, (2R)-
vitamin
A-TOCOPHEROL
Irganox E 201
(2R)-2,5,7,8-Tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-6-chromanol
MFCD00072051
DL-VITAMIN E
dl-Alpha-Tocopherol
EINECS 233-466-0
DL-α-Tocopherol
(+/-)-alpha-Tocopherol,synthetic

Biological Activity

[Description]:

DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kondo S, et al. Protective effect of dl-alpha-tocopherol on the cytotoxicity of ultraviolet B against human skin fibroblasts in vitro. Photodermatol Photoimmunol Photomed. 1990 Aug;7(4):173-7.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
485.9±0.0 °C at 760 mmHg

[ Melting Point ]:
2-4°C

[ Molecular Formula ]:
C₂₉H₅₀O₂

[ Molecular Weight ]:
430.706

[ Flash Point ]:
210.2±24.4 °C

[ Exact Mass ]:
430.381073

[ PSA ]:
29.46000

[ LogP ]:
11.90

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.495

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GA8746000

CHEMICAL NAME :: 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-

CAS REGISTRY NUMBER :: 10191-41-0

BEILSTEIN REFERENCE NO. :: 0094012

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C29-H50-O2

MOLECULAR WEIGHT :: 430.79

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 2500 ug/kg

REFERENCE :: CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 25,163,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1133 No. of Facilities: 104 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 555 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1133 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 114 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
GA8746000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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