DL-alpha-Tocopherol

Names

[ CAS No. ]:
59-02-9

[ Name ]:
DL-alpha-Tocopherol

[Synonym ]:
Viterra E
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
Juvela Food 500
Med-E
Denamone
D-a tocopherol
(2R,4'R,8'R)-a-Tocopherol
Renascin
a-Tocopherol
Syntopherol
[2R-2R*(4R*,8R*)]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
Tokopharm
α-Tokoferol
EINECS 200-412-2
Profecundin
(+)-α-tocopherol
Etavit
Rontex 201
Rocavit E
Vascuals
Epsilan
Lan-E
(2R,4'R,8'R)-2,5,7,8-Tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol
Tenox GT 1
VITEOLIN
(all-R)-α-Tocopherol
Fujimix E 20N
(R,R,R)-a-Tocopherol
Phytogermine
Etamican
Viprimol
(2R,4'R,8'R)-α-Tocopherol
(R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-ol
Almefrol
Endo E
MFCD00072045
α-Tocopherol
Irganox E 217
Irganox E 218
D-α tocopherol
Vitamin E α
Esorb
D-α-Tocopherol
Rhenogran Ronotec 50
(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-6-chromanol
(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL
Aquasol E
Vitaplex E
Juvela E
Erevit forte
α-Tocopherol acid
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
Vitamin E
Vi-E
E-Mix 40
(all-R)-a-Tocopherol
Antisterility vitamin
Covitol
E Prolin
Palmvitee
Verrol
Emipherol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-
a-Tocopherol Acid
Irganox E 201
Ilitia
Spavit E
covi-ox
E-Oil 1000
(+)-a-Tocopherol
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol
Covitol F 1300
Vitayonon
Hydrovit E forte
Juvela nicotinate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, (2R)-
a-Tokoferol
(+)-alpha-tocopherol

Biological Activity

[Description]:

(+)-α-Tocopherol is a vitamin E derivative. vitamin E is a fat-soluble antioxidant.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Natural Products >> Others

Research Areas >> Cancer

Research Areas >> Infection

[References]

[1]. Geissler RG, et al. In vitro improvement of bone marrow-derived hematopoietic colony formation in HIV-positive patients by alpha-D-tocopherol and erythropoietin. Eur J Haematol. 1994 Oct;53(4):201-6.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
485.9±0.0 °C at 760 mmHg

[ Melting Point ]:
2.5-3.5ºC

[ Molecular Formula ]:
C₂₉H₅₀O₂

[ Molecular Weight ]:
430.706

[ Flash Point ]:
210.2±24.4 °C

[ Exact Mass ]:
430.381073

[ PSA ]:
29.46000

[ LogP ]:
11.90

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.495

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ2900000

CHEMICAL NAME :: 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltr idecyl)-, (2R-(2R*(4R*,8R*)))-

CAS REGISTRY NUMBER :: 59-02-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C29-H50-O2

MOLECULAR WEIGHT :: 430.79

WISWESSER LINE NOTATION :: T66 BOT&J C3Y1&3Y1&3Y1&1 C1 G1 HQ I1 J1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 7500 mg/kg

SEX/DURATION :: female 1-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

TYPE OF TEST :: DNA adduct

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 100 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 45,337,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5582 No. of Facilities: 279 (estimated) No. of Industries: 4 No. of Occupations: 8 No. of Employees: 6957 (estimated) No. of Female Employees: 3599 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
DJ2900000

[ HS Code ]:
2936280000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

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