ROCK1-IN-1

Names

[ CAS No. ]:
692869-38-8

[ Name ]:
ROCK1-IN-1

[Synonym ]:
MFCD06338963

Biological Activity

[Description]:

ROCK1-IN-1 is a ROCK1 inhibitor with a Ki value of 540 nM. ROCK1-IN-1 can be used for the research of hypertension, glaucoma and erectile dysfunction[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK
Signaling Pathways >> Stem Cell/Wnt >> ROCK
Signaling Pathways >> TGF-beta/Smad >> ROCK

[References]

[1]. Green J, et al. Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors. J Med Chem. 2015 Jun 25;58(12):5028-37.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H15N3O2S

[ Molecular Weight ]:
325.38

Related Compounds