Mcl1-IN-3

Names

[ CAS No. ]:
1814891-79-6

[ Name ]:
Mcl1-IN-3

Biological Activity

[Description]:

Mcl1-IN-3 is an inhibitor of Mcl1 extracted from patent WO2015153959A2, compound example 57; has an IC50 and Ki of 0.67 and 0.13 μM, respectively.

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family
Research Areas >> Cancer

[Target]

IC50: 0.67 μM (Mcl1)[1] Ki: 0.13 μM (Mcl1)[1]


[References]

[1]. Nikolovska-Coleska Z, et al. Pyrazolopyridines as inhibitors of Mcl-1 and and their preparation. WO2015153959A2


[Related Small Molecules]

Venetoclax (ABT-199) | ABT-263 | S63845 | ABT-737 | Obatoclax Mesylate | A-1210477 | A-1155463 | WEHI-539 hydrochloride | A-1331852 | Bax inhibitor peptide V5 | FX 1 | Gambogic Acid | TW-37 | UMI-77 | Acetate gossypol

Chemical & Physical Properties

[ Molecular Formula ]:
C27H22ClN3O4

[ Molecular Weight ]:
487.93

Related Compounds