Mcl1-IN-4

Names

[ CAS No. ]:
1580484-04-3

[ Name ]:
Mcl1-IN-4

Biological Activity

[Description]:

Mcl1-IN-4 is an inhibitor of Mcl1 with an IC50 of 0.2 μM.

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family
Research Areas >> Cancer

[Target]

IC50: 0.2 μM (Mcl1)[1]


[In Vitro]

Mcl1-IN-4 is compound 19[1].

[References]

[1]. Petros A, et al. Fragment-based Discovery of Potent Inhibitors of the Anti-Apoptotic MCL-1 Protein. Bioorg Med Chem Lett, 24 (6), 1484-1488.


[Related Small Molecules]

Venetoclax (ABT-199) | ABT-263 | S63845 | ABT-737 | Obatoclax Mesylate | A-1210477 | A-1155463 | WEHI-539 hydrochloride | A-1331852 | Bax inhibitor peptide V5 | FX 1 | Gambogic Acid | TW-37 | UMI-77 | Acetate gossypol

Chemical & Physical Properties

[ Molecular Formula ]:
C28H26N2O5S

[ Molecular Weight ]:
502.58

Related Compounds