FAAH-IN-5

Names

[ CAS No. ]:
1338575-38-4

[ Name ]:
FAAH-IN-5

Biological Activity

[Description]:

FAAH-IN-5 (Compound 7) is a relative selective, irreversible fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 10.5 nM. FAAH-IN-5 shows low PAMPA (Parallel Artificial Membrane Permeability Assay) permeability[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL
Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH
Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> FAAH

[Target]

IC50: 10.5 nM (FAAH), 283 nM (MAGL)[1]


[References]

[1]. Alan Fulp, et al. Design and synthesis of endocannabinoid enzyme inhibitors for ocular indications. Bioorg Med Chem Lett. 2022 Jul 15;68:128763.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H19N3O6S

[ Molecular Weight ]:
441.46

Related Compounds