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PD 117519

Names

[ CAS No. ]:
96392-15-3

[ Name ]:
PD 117519

[Synonym ]:
N-[(1R)-2,3-Dihydro-1H-inden-1-yl]-adenosine
N6-[1-(R)-indanyl]adenosine
(R)-N-(2,3-dihydro-1H-inden-1-yl) adenosine
PD 117519

Biological Activity

[Description]:

PD 117519 is an adenosine agonist.Target: Adenosine ReceptorPD 117519 is an adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Research Areas >> Neurological Disease

[References]

[1]. Reynolds DL, et al. Liquid chromatographic analysis of the adenosine agonist PD 117519 in dog plasma. J Pharm Biomed Anal. 1991;9(4):345-9.


[Related Small Molecules]

CGS 21680 hydrochloride | Preladenant | ZM 241385 | CPI-444 | SCH 58261 | Vipadenant | Istradefylline | Tozadenant | AZD-4635 | Capadenoson | 2-CL-IB-MECA | PSB-12379 | CD73-IN-1 | IB-MECA | Diprophylline

Chemical & Physical Properties

[ Density]:
1.71g/cm3

[ Boiling Point ]:
723.3ºC at 760 mmHg

[ Molecular Formula ]:
C19H21N5O4

[ Molecular Weight ]:
383.40100

[ Flash Point ]:
391.2ºC

[ Exact Mass ]:
383.15900

[ PSA ]:
125.55000

[ LogP ]:
0.61020

[ Index of Refraction ]:
1.821

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds