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Morinidazole

Names

[ CAS No. ]:
92478-27-8

[ Name ]:
Morinidazole

[Synonym ]:
TUPWG40JAL
1-(2-Methyl-5-nitro-1H-imidazol-1-yl)-3-(4-morpholinyl)-2-propanol
4-Morpholineethanol, α-[(2-methyl-5-nitro-1H-imidazol-1-yl)methyl]-

Biological Activity

[Description]:

Morinidazole is a novel 5-nitroimidazole antimicrobial drug that undergoes extensive metabolism in humans via N+-glucuronidation and sulfation, for the treatment of bacterial infections including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial
Research Areas >> Infection

[References]

[1]. Zhong K, et al. Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearanceof the conjugated metabolites. Antimicrob Agents Chemother. 2014 Jul;58(7):4153-61.


[Related Small Molecules]

Puromycin 2HCl | Geneticin | Tunicamycin | Hygromycin B | Salinomycin | Avibactam sodium | Neomycin sulfate | Vaborbactam | Methicillin SodiuM | Rifampicin | Metronidazole | Carbenicillin disodium | Ceftazidime | Eravacycline dihydrochloride | cefotaxime sodium

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
521.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H18N4O4

[ Molecular Weight ]:
270.285

[ Flash Point ]:
269.2±30.1 °C

[ Exact Mass ]:
270.132813

[ LogP ]:
0.46

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.632

Related Compounds

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